Heming Li | Molecular Biology | Research Excellence Award

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Dr. Heming Li | Molecular Biology | Research Excellence Award

Doctor | The first hospital of China Medical University | China

Dr. Heming Li is an oncology clinician-scientist whose research has generated 1,045 citations across 37 scientific documents with an h-index of 17, reflecting a sustained impact on translational cancer science. His work centers on liquid biopsy innovations, particularly circulating tumor cells (CTCs), tumor invasion and metastasis, and immunotherapy biomarkers in lung, gastric, and hepatobiliary cancers. Dr. Li is recognized for pioneering one of China’s earliest and most sensitive cell-surface vimentin (CSV)–based CTC detection platforms, integrating negative and positive enrichment to enhance diagnostic accuracy, reduce costs, and enable real-time monitoring of tumor evolution. His research spans EMT regulation, immune escape, metabolic reprogramming, and multi-omics characterization of metastatic pathways, leading to first-author and corresponding-author publications in high-impact journals such as The Lancet, Journal of Hematology & Oncology, Journal of Experimental & Clinical Cancer Research, Molecular Cancer, Cancer Letters, and Cell Death & Disease. He has elucidated mechanisms including IGF-IR signaling, KDM4A/STAT3-driven tumor progression, ICAM-1-mediated microenvironmental adaptation, and PD-L1 expression on CSV⁺ CTCs as a prognostic marker in gastric cancer. His recent studies have also advanced understanding of FGL1 as an immune checkpoint target and the biological significance of TROP2 in cancer therapeutics. As principal investigator, he has secured major national and provincial funding, including NSFC General and Young Programs, to study CTC-based biomarkers, immunotherapy prediction models, and metastasis-driving pathways. Through sustained contributions across liquid biopsy technology, molecular oncology, and clinically actionable biomarker development, Dr. Li has established a leading research profile shaping the future of precision cancer care.

Profile: Scopus  

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Wenhe Lin | Genetics | Best Researcher Award

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Dr. Wenhe Lin | Genetics | Best Researcher Award

Wenhe Lin | University of Chicago | United States

Dr. Wenhe Lin is a researcher affiliated with the Department of Human Genetics at The University of Chicago, United States, whose scientific work focuses on uncovering the genetic and molecular mechanisms that regulate physiological responses to diet and environmental factors. His research contributes to a deeper understanding of how gene expression adapts to metabolic stress, offering insights into the biological foundations of complex diseases. Dr. Lin has published one peer-reviewed article titled “Genetic regulatory effects in response to a high-cholesterol, high-fat diet in baboons,” which appeared in Cell Genomics. This study highlights the interplay between nutrition and genetic regulation, addressing critical questions in metabolic and nutritional genomics. According to his Scopus author profile, Dr. Lin has authored 1 scientific document, which has received 10 citations, and maintains an h-index of 1, reflecting the early yet impactful nature of his academic contributions. His research approach integrates genomic sequencing, bioinformatics, and systems biology to explore gene–environment interactions that influence disease susceptibility. At The University of Chicago, he continues to advance research in human genetics with an emphasis on precision health and individualized nutrition strategies. Dr. Lin’s emerging body of work demonstrates strong potential to shape future investigations into metabolic regulation, genetic variability, and their implications for personalized medicine and human health.

Profiles: ORCID | Scopus | Google Scholar

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