Mr. Hamid Madanchi | Bioinformatics in Lab Medicine | Editorial Board Member

Assistant Professor | Semnan University of Medical Sciences | Iran

Dr. Hamid Madanchi, Ph.D., is an Assistant Professor of Pharmaceutical Biotechnology at the Semnan University of Medical Sciences and an active researcher at the Pasteur Institute of Iran. His multidisciplinary research integrates pharmaceutical biotechnology, bioinformatics, immunoinformatics, and peptide-based drug design to develop novel therapeutics and vaccines. With extensive expertise in molecular cloning, protein engineering, computational biology, and antimicrobial peptide synthesis, Dr. Madanchi’s work focuses on the discovery and rational design of bioactive peptides with anticancer, antimicrobial, and antiviral properties. His recent investigations include the development of SARS-CoV-2 fusion inhibitors, multi-epitope vaccines against emerging pathogens, and nanobiocomposite scaffolds for biomedical applications. Dr. Madanchi has authored and co-authored numerous peer-reviewed articles in high-impact journals such as Journal of Biomolecular Structure and Dynamics, Scientific Reports, Probiotics and Antimicrobial Proteins, and BMC Bioinformatics. His scientific contributions also include studies on peptide-based drug delivery systems, targeted cancer therapies, and computational vaccine design. As principal investigator on multiple national research projects, he has led efforts in epitope-based vaccine construction, antiviral peptide discovery, and bioinformatics-driven drug repurposing. Beyond research, Dr. Madanchi has played an important role in mentoring graduate students and advancing pharmaceutical biotechnology education in Iran. His ongoing work continues to bridge experimental and computational methods for the discovery of next-generation therapeutic biomolecules addressing global health challenges.

Profile: ORCID

Featured Publications

1. Yamchi, A., Madanchi, H., Khazaei, V., Behrouzikhah, M., Abbasi, H., Salehi, M., Moradi, N., & Sanami, S. (2024). Designing a multi-epitope vaccine against the SARS-CoV-2 variant based on an immunoinformatics approach. Current Computer-Aided Drug Design, 20(3), 274–290.

2. Lahimchi, M. R., Madanchi, H., Ahmadi, K., Shahbazi, B., & Yousefi, B. (2024). In silico designing a novel TLR4-mediating multiepitope vaccine against monkeypox via advanced immunoinformatics and bioinformatics approaches. Journal of Biomolecular Structure and Dynamics, 42(4), 2094–2110.

3. Khadijeh, A., Farasat, A., Rostamian, M., Johari, B., & Madanchi, H. (2021). Enfuvirtide, an HIV-1 fusion inhibitor peptide, can act as a potent SARS-CoV-2 fusion inhibitor: An in silico drug repurposing study. Journal of Biomolecular Structure and Dynamics.

4. Eivazzadeh-Keihan, R., Radinekiyan, F., Aliabadi, H. A. M., & Madanchi, H. (2021). Chitosan hydrogel/silk fibroin/Mg(OH)₂ nanobiocomposite as a novel scaffold with antimicrobial activity and improved mechanical properties. Scientific Reports, 11, 650.

5. Madanchi, H., Kiasari, R. E., Mousavi, S. J., Johari, B., Shabani, A. A., & Sardari, S. (2020). Design and synthesis of lipopolysaccharide-binding antimicrobial peptides based on truncated rabbit and human CAP18 peptides and evaluation of their action mechanism. Probiotics and Antimicrobial Proteins, 12(3), 853–864.

Hamid Madanchi | Bioinformatics in Lab Medicine | Editorial Board Member

Mr. Hamid Madanchi | Bioinformatics in Lab Medicine | Editorial Board Member

Featured Publications

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