Mingjie Wei | Biochemistry | Best Researcher Award

Dr. Mingjie Wei | Biochemistry | Best Researcher Award

Doctor at Hubei University of Science and Technology, China

Dr. Mingjie Wei is a dedicated researcher and innovator in the fields of fluorescence sensors, bioimaging, organocatalysis, and drug design. With a solid foundation in chemistry and years of progressive experience across academic and industrial research settings, Dr. Wei has made meaningful contributions to chemical sciences. His research efforts are underscored by high-impact publications, patents, and leadership roles, positioning him as a promising figure in modern chemical innovation and translational science.

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Education

Dr. Wei began his academic journey in chemistry at Hainan University, where he earned his bachelor’s degree in 2010 under the supervision of Prof. Shiming Deng. He then pursued a master’s degree at Hunan Normal University, graduating in 2013, under the mentorship of Prof. Youyu Zhang and as part of Academician Yao Shouzhuo’s prestigious research team. His doctoral studies were completed at Sun Yat-sen University in 2021, where he worked under Prof. Le Li, focusing on cutting-edge topics in organocatalysis and fluorescence-based detection techniques.

Experience

Dr. Wei’s professional trajectory spans both academia and industry. He is currently a postdoctoral researcher at Guangzhou University under the guidance of Prof. Li Niu (since May 2024). Prior to this, he served as a high-level faculty member and master’s supervisor at Hubei University of Science and Technology from 2022, playing a critical role in teaching and mentoring graduate students. His industrial experience includes serving as R&D Director at Dongguan Biotechnology Development Co., Ltd. (2021–2022) and Project Manager at HEC Pharmaceutical Industry (2013–2016), where he led the development of several innovative drug and sensor technologies. He also contributed as a research assistant at Sun Yat-sen University (2016–2017), building further expertise in analytical chemistry.

Research Interest

Dr. Wei’s research interests are rooted in interdisciplinary chemistry. He focuses on fluorescence sensors and bioimaging, particularly for real-time detection of biological and environmental targets. His work also delves into organocatalysis and rational drug design, combining synthetic chemistry with molecular diagnostics. Through novel probe development and mechanistic studies, he aims to bridge the gap between chemical innovation and biomedical applications. His projects often emphasize sensitivity, selectivity, and biocompatibility—key metrics for translational success.

Award

Dr. Wei has been recognized for his academic and scientific excellence through multiple competitive grants and fellowships. These include the prestigious China Postdoctoral Science Foundation Award (2024M760620), Hubei Science and Technology Program grant (2022CFB781), and a Doctoral Startup Fund Project from Hubei University of Science and Technology. Additionally, he leads a university-level teaching reform project, further demonstrating his commitment to pedagogical excellence alongside research.

Publication

Dr. Wei has authored multiple peer-reviewed articles in high-impact journals. Below are seven select publications, showcasing his diverse research contributions:

Chem. Eng. J. (2025) – Co-authored a study on nanomaterials for environmental detection, cited by 12 articles.

Sci. China Chem. (2025) – Investigated advanced fluorescence probes, cited by 9 articles.

J. Colloid Interface Sci. (2025) – Developed biosensing platforms with clinical relevance, cited by 6 articles.

J. Colloid Interface Sci. (2023) – Explored novel colloidal interactions for sensor enhancement, cited by 18 articles.

Angew. Chem. Int. Ed. (2021) – Contributed to catalyst development for selective transformations, cited by 27 articles.

Spectrochim. Acta A (2024) – Published on spectroscopic methods in analyte detection, cited by 5 articles.

Anal. Methods (2017) – Designed a fluorescence-based method for metal ion detection, cited by 22 articles.

These publications reflect Dr. Wei’s consistent scholarly output and his ability to address diverse challenges in analytical and synthetic chemistry.

Conclusion

Dr. Mingjie Wei exemplifies the qualities of a distinguished researcher — scientific excellence, innovative spirit, and a commitment to translational impact. His robust academic foundation, rich professional experience, and outstanding scholarly output position him as a highly deserving candidate for the Best Researcher Award. Recognizing Dr. Wei would not only honor his individual achievements but also encourage continued innovation in chemical and biomedical sciences.

 

Xuexiang Han | Organic Chemistry | Best Researcher Award

Prof. Dr.Xuexiang Han | Organic Chemistry | Best Researcher Award

Professor at Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, China

Professor Xuexiang Han is a prominent researcher in the field of nanomedicine and RNA delivery systems. Currently serving as a Professor at the Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, he has significantly contributed to the development of ionizable lipid nanoparticles for RNA-based therapeutics. With a deep commitment to translating chemical innovation into biomedical application, his work bridges the disciplines of chemistry, bioengineering, and molecular biology. Professor Han’s research addresses crucial challenges in drug delivery, aiming to treat diseases ranging from cancer to infectious and genetic disorders through advanced nanotechnology.

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Education

Professor Han’s academic foundation was built at Shanghai University, where he earned a Bachelor of Engineering in Chemical Engineering in 2014. He then pursued doctoral studies at Tsinghua University, one of China’s premier institutions, where he obtained a Ph.D. in Chemistry in 2019. His doctoral work was conducted in collaboration with the National Center for Nanoscience and Technology in Beijing under the co-supervision of Professors Yuliang Zhao and Yadong Li. This interdisciplinary training provided him with the expertise necessary to tackle complex problems at the interface of chemistry and biology, particularly in the design of nanomaterials for biomedical use.

Experience

Following his Ph.D., Professor Han joined the Department of Bioengineering at the University of Pennsylvania as a postdoctoral researcher from January 2020 to January 2024. Under the mentorship of Professor Michael J. Mitchell, he focused on the optimization of lipid nanoparticles for RNA delivery. His work during this period was instrumental in advancing the development of next-generation mRNA vaccines and therapeutic agents. Since February 2024, he has held a faculty position as a Professor at the Chinese Academy of Sciences, where he leads a research group focused on innovative RNA delivery strategies.

Research Interests

Professor Han’s research is centered on the design and synthesis of ionizable lipid nanoparticles (LNPs) for the delivery of RNA therapeutics. His group develops combinatorial chemistries to create novel lipid structures that enhance the delivery, potency, and safety of mRNA and other nucleic acids. Applications of his research span mRNA vaccines, gene editing, and targeted therapy for cancers and genetic diseases. By integrating in vitro and in vivo screening methodologies, Professor Han seeks to refine these delivery systems for both local and systemic administration, with a focus on overcoming biological barriers to RNA delivery.

Award

Professor Han’s scientific excellence has been recognized with numerous awards. In 2023, he was honored as a Young Overseas High-Level Talent of China, a prestigious recognition for emerging leaders in science and technology. Earlier, he received the President Prize of the Chinese Academy of Sciences for Excellent Ph.D. Graduates in 2019 and the National Scholarship of China in 2018. These accolades highlight his ongoing contributions to scientific advancement and his potential to lead groundbreaking research in the coming years.

Publication

Among Professor Han’s extensive publication record, several standout articles have garnered significant citations and recognition. Notable works include:

Han X. et al., “Optimization of the activity and biodegradability of ionizable lipids for mRNA delivery via directed chemical evolution,” Nat. Biomed. Eng., 2024, 8:1412 – cited by numerous follow-up studies in synthetic lipid research.

Han X. et al., “Fast and Facile Synthesis of Amidine-Incorporated Degradable Lipids for mRNA Delivery,” Nat. Chem., 2024, 16:1687 – influential in the field of degradable lipid design.

Han X. et al., “In situ combinatorial synthesis of degradable branched lipidoids for mRNA therapeutics,” Nat. Commun., 2024, 15:1762 – a critical reference for gene editing delivery systems.

Han X. et al., “Adjuvant lipidoid-substituted lipid nanoparticles augment SARS-CoV-2 mRNA vaccines,” Nat. Nanotechnol., 2023, 18:1105 – widely cited in vaccine development.

Han X. et al., “Ligand-Tethered Lipid Nanoparticles for Targeted RNA Delivery,” Nat. Commun., 2023, 14:75 – cited for its innovation in liver fibrosis treatment.

Han X. et al., “An Ionizable Lipid Toolbox for RNA Delivery,” Nat. Commun., 2021, 12:7233 – among the top 25 most read articles in Nat. Commun. in 2021.

Han X. et al., “Nanomaterials for Therapeutic RNA Delivery,” Matter, 2020, 3(6):1948 – a comprehensive review frequently cited in the RNA therapeutics community.

Conclusion

In summary, Professor Xuexiang Han exemplifies the attributes of a Best Researcher Award recipient: a visionary scientist, prolific author, dedicated innovator, and impactful academic leader. His pioneering work in RNA nanotechnology and gene therapy has already shaped current biomedical approaches and promises continued influence in years to come. Awarding Professor Han would not only honor his individual achievements but also inspire excellence within the broader scientific community.