Dr. John Lin | Research Methods in Medical Lab Science | Best Researcher Award
Co-CEO | Frontage Laboratories, Inc | United States
Dr. John Lin is a distinguished research scientist affiliated with Frontage Laboratories in Exton, United States. His scientific contributions span analytical chemistry, bioanalysis, and neurodegenerative disease biomarker development. With a total of 30 publications, Dr. Lin’s research has garnered 568 citations, reflecting his consistent impact in the analytical sciences. His h-index of 13 demonstrates both productivity and citation influence across multiple studies. Notably, his recent work, “Validation of an Ultra-Sensitive Method for Quantitation of Phospho-Tau 217 (pTau217) in Human Plasma, Serum, and CSF using the ALZpath pTau217 Assay on the Quanterix HD-X Platform” (Journal of Prevention of Alzheimer’s Disease,), highlights his contribution to Alzheimer’s disease diagnostics. His earlier research includes the development and validation of LC-MS/MS and LC-HRMS methods for protein and antibody–drug conjugate quantification, published in Bioanalysis and Analytical and Bioanalytical Chemistry, respectively. Over his career, Dr. Lin has collaborated with over 230 co-authors, indicating his strong engagement in interdisciplinary research networks. His pioneering work supports precision measurement in clinical and pharmaceutical sciences, particularly enhancing biomarker quantitation technologies. Dr. Lin’s research excellence continues to influence bioanalytical method development and translational applications in clinical laboratory sciences, solidifying his reputation as a leading figure in analytical biochemistry and assay validation research
Profile: Scopus
Featured Publications
1. Lin, Z. (2024). Validation of an ultra-sensitive method for quantitation of phospho-tau 217 (pTau217) in human plasma, serum, and CSF using the ALZpath pTau217 assay on the Quanterix HD-X platform. Journal of Prevention of Alzheimer’s Disease.
2. Lin, Z. (2022). Development and validation of an LC-MS/MS method for the quantification of fascin proteins in human serum. Bioanalysis.
3. Lin, Z. (2020). Accurate determination of drug-to-antibody ratio of interchain cysteine-linked antibody–drug conjugates by LC-HRMS. Analytical and Bioanalytical Chemistry.
4. Lin, Z. (2019). Quantitative bioanalytical method development for biotherapeutics. Journal of Chromatography B.
5. Lin, Z. (2018). Optimization of analytical workflows for protein quantitation in biological matrices. Journal of Pharmaceutical and Biomedical Analysis.