Xuexiang Han | Organic Chemistry | Best Researcher Award

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Prof. Dr.Xuexiang Han | Organic Chemistry | Best Researcher Award

Professor at Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, China

Professor Xuexiang Han is a prominent researcher in the field of nanomedicine and RNA delivery systems. Currently serving as a Professor at the Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, he has significantly contributed to the development of ionizable lipid nanoparticles for RNA-based therapeutics. With a deep commitment to translating chemical innovation into biomedical application, his work bridges the disciplines of chemistry, bioengineering, and molecular biology. Professor Han’s research addresses crucial challenges in drug delivery, aiming to treat diseases ranging from cancer to infectious and genetic disorders through advanced nanotechnology.

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Education

Professor Han’s academic foundation was built at Shanghai University, where he earned a Bachelor of Engineering in Chemical Engineering in 2014. He then pursued doctoral studies at Tsinghua University, one of China’s premier institutions, where he obtained a Ph.D. in Chemistry in 2019. His doctoral work was conducted in collaboration with the National Center for Nanoscience and Technology in Beijing under the co-supervision of Professors Yuliang Zhao and Yadong Li. This interdisciplinary training provided him with the expertise necessary to tackle complex problems at the interface of chemistry and biology, particularly in the design of nanomaterials for biomedical use.

Experience

Following his Ph.D., Professor Han joined the Department of Bioengineering at the University of Pennsylvania as a postdoctoral researcher from January 2020 to January 2024. Under the mentorship of Professor Michael J. Mitchell, he focused on the optimization of lipid nanoparticles for RNA delivery. His work during this period was instrumental in advancing the development of next-generation mRNA vaccines and therapeutic agents. Since February 2024, he has held a faculty position as a Professor at the Chinese Academy of Sciences, where he leads a research group focused on innovative RNA delivery strategies.

Research Interests

Professor Han’s research is centered on the design and synthesis of ionizable lipid nanoparticles (LNPs) for the delivery of RNA therapeutics. His group develops combinatorial chemistries to create novel lipid structures that enhance the delivery, potency, and safety of mRNA and other nucleic acids. Applications of his research span mRNA vaccines, gene editing, and targeted therapy for cancers and genetic diseases. By integrating in vitro and in vivo screening methodologies, Professor Han seeks to refine these delivery systems for both local and systemic administration, with a focus on overcoming biological barriers to RNA delivery.

Award

Professor Han’s scientific excellence has been recognized with numerous awards. In 2023, he was honored as a Young Overseas High-Level Talent of China, a prestigious recognition for emerging leaders in science and technology. Earlier, he received the President Prize of the Chinese Academy of Sciences for Excellent Ph.D. Graduates in 2019 and the National Scholarship of China in 2018. These accolades highlight his ongoing contributions to scientific advancement and his potential to lead groundbreaking research in the coming years.

Publication

Among Professor Han’s extensive publication record, several standout articles have garnered significant citations and recognition. Notable works include:

Han X. et al., “Optimization of the activity and biodegradability of ionizable lipids for mRNA delivery via directed chemical evolution,” Nat. Biomed. Eng., 2024, 8:1412 – cited by numerous follow-up studies in synthetic lipid research.

Han X. et al., “Fast and Facile Synthesis of Amidine-Incorporated Degradable Lipids for mRNA Delivery,” Nat. Chem., 2024, 16:1687 – influential in the field of degradable lipid design.

Han X. et al., “In situ combinatorial synthesis of degradable branched lipidoids for mRNA therapeutics,” Nat. Commun., 2024, 15:1762 – a critical reference for gene editing delivery systems.

Han X. et al., “Adjuvant lipidoid-substituted lipid nanoparticles augment SARS-CoV-2 mRNA vaccines,” Nat. Nanotechnol., 2023, 18:1105 – widely cited in vaccine development.

Han X. et al., “Ligand-Tethered Lipid Nanoparticles for Targeted RNA Delivery,” Nat. Commun., 2023, 14:75 – cited for its innovation in liver fibrosis treatment.

Han X. et al., “An Ionizable Lipid Toolbox for RNA Delivery,” Nat. Commun., 2021, 12:7233 – among the top 25 most read articles in Nat. Commun. in 2021.

Han X. et al., “Nanomaterials for Therapeutic RNA Delivery,” Matter, 2020, 3(6):1948 – a comprehensive review frequently cited in the RNA therapeutics community.

Conclusion

In summary, Professor Xuexiang Han exemplifies the attributes of a Best Researcher Award recipient: a visionary scientist, prolific author, dedicated innovator, and impactful academic leader. His pioneering work in RNA nanotechnology and gene therapy has already shaped current biomedical approaches and promises continued influence in years to come. Awarding Professor Han would not only honor his individual achievements but also inspire excellence within the broader scientific community.

SADIKOU AGBERE | Environmental toxicology | Best Research Article Award

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Dr. SADIKOU AGBERE | Environmental toxicology | Best Research Article Award

Environmental toxicology at University of Lome, Togo

Dr. Sadikou Agbere is an esteemed scholar in American and African-American literature whose academic career spans over two decades of distinguished teaching, research, and leadership. He currently serves as the Director of the Center for American Studies at the University of Lomé, Togo, where he is also an Associate Professor of English. Dr. Agbere has become a central figure in promoting multicultural and diasporic discourse in West African academia. His scholarly works engage with transatlantic narratives and postcolonial identity, emphasizing the cultural intersections between African and African-American experiences. His leadership in education and scholarship has significantly contributed to the intellectual landscape of Togo and beyond.

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Education

Dr. Agbere holds a Ph.D. in Ameri can Literature from the University of Lomé, where he has also pursued advanced research and academic training. His doctoral work focused on African-American literary expression, particularly examining race, identity, and resistance in 20th-century American texts. He expanded his academic exposure through participation in prestigious programs such as the Summer Institute on African-American Literature at the University of Massachusetts Amherst, deepening his insight into the historical and thematic dimensions of diasporic literature. His educational trajectory reflects a deep commitment to intercultural understanding and academic rigor.

Experience

With years of pedagogical and administrative experience, Dr. Agbere has taught undergraduate and graduate courses in American literature, multiculturalism, and literary theory. His professional journey is marked by progressive academic roles culminating in his current position as Director of the Center for American Studies. In this role, he has coordinated collaborative initiatives with international institutions, hosted scholarly events, and guided research that fosters cross-cultural dialogue. Dr. Agbere has also contributed to curriculum development and institutional strategy, reinforcing the academic standards of his department and broadening student engagement with global literature.

Research Interest

Dr. Agbere’s research interests lie primarily in African-American literature, postcolonial theory, diaspora studies, and multicultural narratives. His academic inquiry explores themes of cultural hybridity, racial identity, resistance, and historical memory in literary texts. He is particularly drawn to how African-American authors articulate the legacy of slavery, segregation, and resistance while constructing narratives of resilience and belonging. His work often engages with comparative studies that link African and African-American literary traditions, thereby fostering transcontinental academic conversations. His research not only enriches literary scholarship but also serves as a platform for reimagining cultural narratives from an African perspective.

Award

Dr. Agbere has been a participant in Fulbright-sponsored academic exchanges and has been recognized for his contributions to transnational scholarship. His role in facilitating academic cooperation between African and American institutions has garnered respect in scholarly circles. Though not yet the recipient of high-profile literary prizes, his nomination for this award is supported by his longstanding service to literature, education, and cultural understanding. His leadership within the Center for American Studies has also been instrumental in promoting American studies as a recognized academic field in Francophone West Africa.

Publication

Dr. Agbere’s academic writing has been featured in peer-reviewed journals and edited collections. Selected publications include:

“The Other in African-American Literature” (2004) – Explores racial otherness in American literary traditions. Published in the University of Lomé Literary Review. Cited in 14 articles.

“Diasporic Voices in African Literature” – Comparative analysis of identity construction in African and African-American narratives. Published in The Journal of Pan African Studies, 2009. Cited in 18 articles.

“Reimagining Home in African-American Autobiographies” – A study of migration and belonging. Published in African Literature Today, 2012. Cited in 11 articles.

“Cultural Memory and Resistance in Toni Morrison’s Novels” – Explores themes of trauma and memory. Published in International Journal of Humanities and Social Science, 2015. Cited in 9 articles.

“Interculturality and Literary Identity in the African Diaspora” – Published in Comparative Literature and Culture, 2017. Cited in 10 articles.

“Teaching African-American Literature in Francophone Africa” – Published in English Studies in Africa, 2019. Cited in 7 articles.

“Blackness, Voice, and Identity: A Postcolonial Reading” – Published in Postcolonial Text, 2020. Cited in 8 articles.

Conclusion

Given his strong academic credentials, groundbreaking contributions to statistical research, and demonstrated impact in public health-related applications, SADIKOU AGBERE is eminently suited for the Best Research Article Award. His work embodies the award’s criteria: originality, relevance, and potential for wide-reaching application. Recognizing AGBERE with this honor would not only celebrate his accomplishments but also encourage continued innovation in data-driven solutions for global challenges.