Cara-Lynne Schengrund | Biochemistry | Best Researcher Award

Prof. Dr. Cara-Lynne Schengrund | Biochemistry | Best Researcher Award

Professor | Penn State College of Medicine | United States

Dr. Cara-Lynne Schengrund, Professor Emerita of Biochemistry and Molecular Biology at the Pennsylvania State University College of Medicine, is a distinguished scientist whose career has spanned over four decades. She earned her B.S. in Chemistry from Upsala College and her M.S. and Ph.D. In Chemistry from Seton Hall University, later holding research positions at Columbia University before joining Penn State. Rising through the academic ranks, she served as Assistant Professor, Associate Professor, Professor, and Acting Department Chair, ultimately achieving Emerita status. Her pioneering research has focused on glycosphingolipids and gangliosides, where she made landmark discoveries on their roles in neuronal development, neuroblastoma prognosis, and lipid raft biology, as well as their function as receptors for bacterial toxins and viruses. Her laboratory was the first to develop multivalent oligosaccharide inhibitors that block cholera toxin and HIV binding, establishing new therapeutic strategies. She has also contributed groundbreaking insights into the roles of gangliosides and cholesterol in Alzheimer’s disease and autism, authoring over 200 influential publications in neurochemistry and glycobiology. Beyond research, Dr. Schengrund has been a leader in academic service, serving as Chair of the Penn State Faculty Senate, elected Council Member of the American Society for Neurochemistry, and as a member of NIH and VA study sections. Her honors include the Distinguished Alumni Award from Upsala College and the YWCA Tribute to Women of Excellence. Through her research, mentorship, and leadership, Dr. Schengrund has made a lasting impact on science, medicine, and education.

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Anthia Govender | Medical Biochemistry | Best Researcher Award

Ms. Anthia Govender | Medical Biochemistry | Best Researcher Award

PhD student at University of Kwa-Zulu Natal, South Africa

Anthia Camara Govender is an emerging scientist currently pursuing her PhD in Medical Biochemistry at the University of KwaZulu-Natal. With a strong academic background and early research contributions in toxicology and epigenetics, she has quickly established herself as a promising researcher in the biomedical field. Anthia’s work primarily investigates the cellular and molecular effects of environmental toxins such as mycotoxins, with a specific focus on their impact on lung tissue and genetic regulation. Her dedication to uncovering new insights in medical biochemistry reflects a clear commitment to advancing translational science and therapeutic strategies.

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Education

Anthia’s academic journey began with her matriculation from Sathya Sai School, Chatsworth, in 2019. She obtained her Bachelor’s degree in Medical Science (Physiology) from the University of KwaZulu-Natal in 2022. Her strong academic performance continued as she graduated cum laude in both her Honours in Medical Science (Medical Biochemistry) in 2023 and her Master’s degree in Medical Science (Medical Biochemistry) in 2024. Currently, she is enrolled in a PhD program at the same university, focusing her doctoral research on the toxicological effects of fumonisins on pulmonary epigenetics and cellular dysfunction.

Experience

Although at the early stage of her professional career, Anthia has already undertaken significant research responsibilities through her postgraduate projects. Her Master’s study focused on the impact of Fumonisin B1 (FB1), a harmful mycotoxin, on oxidative stress and DNA methylation in mice lung tissue. The study required detailed laboratory work involving mitochondrial function assays, methylation analysis, and the interpretation of oxidative stress markers. Furthermore, she has been involved in one consultancy-related research project and continues to refine her expertise in toxicology and biochemical pathways relevant to human disease.

Research Interest

Anthia’s research interests are deeply rooted in medical biochemistry, with a focus on toxicology, mycotoxins, epigenetics, and oxidative stress. Her academic progression into PhD-level work demonstrates a growing interest in exploring how environmental toxins disrupt biological systems at a molecular level. She is particularly fascinated by the mechanisms of mitophagy, DNA hypermethylation, and how these contribute to disease pathogenesis. Through her studies, she aims to bridge gaps in current understanding and contribute to the development of therapeutic interventions for toxin-induced diseases.

Award

Anthia has applied for the Best Researcher Award to acknowledge her early but impactful contributions to biomedical research. Her focus on a globally significant issue—mycotoxin exposure—and her successful completion of high-impact research in a short span illustrate her capability and dedication. She has already achieved cum laude status in two advanced degrees, which attests to her academic excellence and potential as a leading scientist in her field.

Publication

Despite being at the beginning of her research career, Anthia has already published one peer-reviewed journal article.

  • Govender AC (2024). “Fumonisin B1-induced Oxidative Stress and DNA Hypermethylation in C57BL6 Mice Lung Tissue.” Journal of Toxicologic Pathology, 37(2): 145–155. [Cited by 2 articles].

This publication investigates the role of FB1 in mitochondrial dysfunction and epigenetic regulation, providing novel insights into toxin-induced lung pathology. The paper has started receiving citations, indicating its relevance in the toxicology research community.

Conclusion

In conclusion, Anthia Camara Govender is a strong candidate for the Research for Best Researcher Award. Her trajectory from undergraduate excellence to emerging PhD researcher has been marked by outstanding academic performance and a research focus with real-world biomedical implications. Her work delves into unexplored aspects of toxicology and epigenetics, providing critical insights into how environmental toxins affect human health. Though at the beginning of her scientific journey, Anthia’s diligence, intellectual curiosity, and research impact underscore her potential as one of the next generation’s leading scientists. Her nomination for this award is both timely and well-deserved.