Assist. Prof. Dr. Véronique LADEVEZE | Molecular Biology | Best Researcher Award

Dr at University of Poitiers, France

Dr. Véronique Ladevèze is an Assistant Professor in Biochemistry, Molecular Biology, and Genetics at the University of Poitiers, France. With over three decades of academic and scientific research experience, she is widely recognized for her work on membrane transporters and genetic mutations related to diseases such as cystic fibrosis and Alzheimer’s. She is affiliated with the MOVE laboratory (UR20296), where she investigates the molecular mechanisms of disease, particularly the roles of CFTR and SLC16a3 genes. Her expertise in alternative splicing and intron retention highlights her contributions to biomarker discovery for aging and neurodegenerative disorders. Dr. Ladevèze is also a committed educator and member of scientific advisory boards, actively mentoring students and contributing to biomedical education. She has participated in high-impact collaborative studies and serves on the Scientific Council of “Vaincre la Mucoviscidose,” supporting research and advocacy for cystic fibrosis. Her dedication to both science and society makes her a standout in her field.

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Education

Dr. Ladevèze has pursued a strong academic foundation in life sciences and genetics. She earned her Doctorate (Ph.D.) in Biochemistry from the University of Poitiers, where her research focused on molecular aspects of human diseases. She previously completed a DEA (Diplôme d’Études Approfondies) in Biomembranes, giving her a specialized foundation in membrane biology and protein transport. Her Master’s degree in Genetics from the University of Paris XI further deepened her knowledge in hereditary diseases, setting the groundwork for her later research into mutations and polymorphisms in key transport genes. She also holds credentials qualifying her to lead independent research from the University of Paris X. Her academic background spans the intersection of molecular biology, cell physiology, and genetic regulation, which informs both her teaching and innovative research on transport proteins and genetic biomarkers.

Experience

Dr. Véronique Ladevèze has extensive experience in both academic research and university-level teaching. She began her academic career as a Lecturer at the University of Tours before joining the University of Poitiers, where she currently serves as Assistant Professor. Over the past 30+ years, she has specialized in studying disease-related membrane transporters such as CFTR (cystic fibrosis) and SLC16a3 (Alzheimer’s and aging). Her experience includes advanced molecular techniques in genomics, splicing analysis, and mutation profiling. She has collaborated with major French and international institutions and has served as a scientific expert for “Vaincre la Mucoviscidose,” a leading organization combating cystic fibrosis. She contributes actively to educational programs at both undergraduate and postgraduate levels and is involved in supervising research students. Her interdisciplinary work bridges laboratory discovery with translational insights into human disease.

Awards and Honors

Dr. Ladevèze has received significant academic and professional recognition throughout her career. She was awarded the title “Hors Classe” with exceptional step status in 2017—an honor conferred in the French academic system for distinguished service and scholarly excellence. She has been a Scientific Council Member of “Vaincre la Mucoviscidose” from 2018 to 2024, where she plays a pivotal advisory role in guiding research direction on cystic fibrosis. Her expertise is frequently sought for evaluations and scientific panels, underscoring her leadership in the biomedical research community. In addition to peer-reviewed publications, she contributes to science communication and public health awareness, especially in the area of genetic diseases. These honors reflect her consistent dedication to advancing research and improving clinical understanding of complex genetic disorders through her pioneering work in transporter biology and splicing mechanisms.

Research Focus

Dr. Ladevèze’s research centers on membrane transporters, specifically the ABC (e.g., CFTR) and SLC (e.g., SLC16a3/MCT4) protein families. Her early work contributed to understanding how rare mutations in CFTR affect protein function and disease severity in cystic fibrosis, one of the most common rare genetic disorders. More recently, her focus has shifted to alternative splicing and intron retention, particularly in the SLC16a3 gene, which may play a role in Alzheimer’s disease and brain aging. She studies how these molecular changes act as potential biomarkers of neurodegenerative stress and dysfunction. Using models like APP/PS1 mice, she explores how transcript variants influence the expression of MCT4 in aging brain tissue. Her interdisciplinary research integrates molecular genetics, neuroscience, and cellular biology, contributing valuable insights into both rare and complex diseases. Her work is highly translational, with implications for diagnostics and personalized medicine.

Skills

Dr. Véronique Ladevèze possesses a comprehensive skill set that bridges advanced research, teaching, and collaboration. As a scientific leader, she has coordinated projects focused on gene transporters, guiding interdisciplinary teams in exploring disease mechanisms. Her expertise in molecular biology and genetics includes mutation analysis, splicing regulation, RT-PCR, and gene expression profiling, particularly applied to cystic fibrosis and neurodegenerative diseases. Fluent in both French and English, she engages effectively in international research collaborations. In academia, she teaches undergraduate and master’s courses in biohealth and actively mentors students in laboratory research. Dr. Ladevèze has a strong record of publishing in peer-reviewed journals and contributes regularly to academic discussions and conferences. She also serves on scientific advisory boards, providing critical peer evaluations and promoting high research standards. Her focus on disease-driven investigation, particularly involving aging and Alzheimer’s biomarkers, highlights her commitment to impactful, translational science that addresses complex medical challenges.

Publications

• CFTR mutation combinations producing frequent complex alleles with different clinical and functional outcomes
  Authors: El-Seedy A., Girodonne A., Norez C., Pajato J., Pasquet M.-C., de Becdelievre A., Bienvenu T., des Georges M., Cabet F., Halau G., Bieth E., Blayau M., Becq F., Kitzis A., Fanen P., Ladevèze V.
  Year: 2012
  Journal: Human Mutation, Volume 33, Issue 11, Pages 1557–1565
  Citations: 4

• Identification of Intron Retention in the Slc16a3 Gene Transcript Encoding the Transporter MCT4 in the Brain of Aged and Alzheimer-Disease Model (APPswePS1dE9) Mice
  Authors: El-Seedy A., Pellerin L., Page G., Ladevèze V.
  Year: 2023
  Journal: Genes, Volume 14, Issue 10, Article 1949
  Citations: 4

Conclusion

Dr. Véronique Ladevèze is a highly qualified candidate for a Best Researcher Award, especially within a biomedical or genetic research context. Her long-standing commitment to impactful, disease-oriented research and academic mentorship strongly supports her candidacy. While some improvements in international visibility and external funding could strengthen her profile further, her body of work already demonstrates excellence in research, innovation, and service to the scientific community.